F1Ch10 (112942): The epidermis shows hypergranulosis. Individual cells in both the superficial and basal units show dyskeratosis; even occasional basal cells show increased cytoplasmic acidophilia. Some of the keratinocytes that are dyskeratotic also show perinuclear vacuoles. Focally, the basement membrane is coarsened and hyalinized; there are areas of liquefaction degeneration. Much of the fibrous component, from the center of the field to the right, has the qualities of reduplicated basement membrane material. Some to the cells in the dermis near the D-E interface are encircled by this material. The material focally loops about one or several cells at the D-E interface. Many of the cells appear to be histiocytes. In essence, the pattern is a variation of changes seen in a lichenoid reaction. There are scattered dendritic cells but it is difficult to identify a convincing melanocyte.
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