F5Ch14 (see also F2Ch14): in this area of epithelial hyperplasia, some of the thin cords at their extremities show basaloid qualities (germinative qualities [red arrows]). Scattered pale pink bodies in the myxoid stroma near the epidermis on the left are interpreted as colloid bodies; in areas, the stromal component has eroded the basal layer of the epidermis.
The patterns provide evidence of the interaction between the germinative portion (i.e., basal unit) of squamous epithelium and activated stroma (with myxoid stroma as an example of activated stroma); the two components expand in mutually accommodating patterns. In this field in the area with the red arrows, the basal unit of the epidermis has taken on basaloid qualties with an accentuation of the basal row of palisaded cells. In turn, the neighboring stroma is somewhat hypercellular and the nuclei of the respective stromal cells are enlarged.
The epithelial patterns might be dismissed as evidence of the “mantle change.” The exuberance of the epithelial strands might be evidence of a lack of success in a search for a proper nerve that, if encountered, would, in turn, lead to the formation of a developing hair bulb.
As one additional consideration, the strands of squamous cells - as opposed to the focus of basal cell transformation - might be evidence of tricholemmal type epithelium awaiting the formation of a trichogenic hair bulb.
The role of the “hair disk” in the development of “trichodiscoma” (F5Ch11) is mostly fanciful. Myxoid change is an optional functional attribute of fibrous tissue, particularly the specialized form that qualifies as stroma, such as the adventitial dermis.