Ch22P14-L3 Catagen-like Tumor & 
Sebaceous Epithelioma

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1. Histopathology of Inflammation

2. Minimal Deviation Melanoma, etc.


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F1Ch22 (G8391): The tumor is in continuity with an epidermis showing irregular acanthosis and mild papillomatosis; there is mild cytologic atypia in the squamous cell component.


F2Ch22: Thin, irregular cords of basophilic cells are supported by delicate, myxoid stroma. Blue arrows identify microcystic components. Hyaline deposits in the stroma, adjacent to some of the nests, are interpreted as amyloid deposits.


F3Ch22: Blue arrows identify the microcystic patterns. Some of the small cysts are outlined by cells that have acidophilic cytoplasm. At the bottom of the field, some of the cells outlining a lumen are clearly sebaceous cells. The amyloid deposits are a prominent feature.


F4Ch22 (G8391) The basic pattern is that of a well-differentiated basal cell carcinoma. The areas of sebaceous differentiation qualify the lesion as a sebaceous epithelioma arising in an irritated seborrheic keratosis.


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