Ch24P16-L3 Tricholemmoma
(blastematous component)

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F1Ch24 (P1112): In this field, there is a well-developed peripheral row of palisaded, columnar cells; the palisaded cells are germinative cells of basal type. A hyaline membrane separates the palisade of cells from the neighbor stroma (small red arrow). The hyaline membrane is lightly stained (section has faded); it corresponds to the glassy membrane of the outer root sheath of an anagen follicle. There are several whorls of pale keratinocytes (variations of squamous eddies). The cells among the whorls are pale and spindle shaped. Squamous eddies, for most structures and most neoplasms, are markers for sites that have the potential to cavitate; in the act, a lumen will be formed. Near the top of the field, the cells are more polygonal and some of the cells have vacuolated (clear) cytoplasm.


F2Ch24 (P1112): A column of basal cells (a blastomatous component) of germinative type projects from the lower margin of a portion of the tumor. The projection is in continuity with the inconstant portion of a miniaturized follicle. (see F1 & F2 of Ch25). In consideration of the basic nature of the tumor and the location of the nest of germinative basal cells, the nest of basal cells might be thought of as a “bulge” in a germinative phase.

 In chapters 39a, 39b, & 39c, the features of sclerosing entrapment, as encountered in the follicular hamartomas of the butterfly area of the face, are discussed. Also in chapter 39a (F5-7), a variant feature, lymphoepithelial change, is discussed.



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