Ch37P29-L4 Giant Pore

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F1Ch37 (G5605): A portion of an epidermoid cyst is represented. This portion was in the dermis and extended close to the epidermis on the available material. The lumen is expanded but a follicular configuration is maintained (there is a vertical orientation). The lining of the cyst is in keeping with the lining of an epidermoid cyst and, although hyperplastic, is similar to the epithelium of the infundibular portion of a normal follicle. The keratinized debris is loosely laminated. Focally, strands of the epithelium (each strand showing the characteristics of the basal unit of the epidermis) extend from the wall of the distorted follicle into a widened perifollicular sheath. The fascicle of smooth muscle to the right represent a portion of the arrector muscle of the follicle. As represented on this section, the changes are compatible with giant pore. On the other hand, this is an eccentric component of what was an epidermoid cyst in the deeper tissue. This combination of features is not uncommon, if the dimple over an epidermoid cyst is included in the section which is to be submitted for histologic examination.

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F2Ch37 (H7009): This is a second example of an epidermoid cyst with a pore. The lumen and the epithelial lining of a pore that communicated at one extremity with the surface of the skin and, at the other extremity, with the lumen of an epidermoid cyst is represented. To the right the epithelial patterns overlap with those of a “giant pore.”

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F3Ch37: The “pore” is represented to the right; the cyst is to the left. The lumens of the cyst and the pore are confluent.

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F4Ch37: The hyperplastic epithelium of the “pore” is represented. The preponderant cell is a plump, pale squamous cell of the type found in the superficial unit of the epidermis. A basal unit is not well-developed. Near the small, keratin-filled cyst on the left, many of the squamous cells show evidence of dyskeratosis.

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F5Ch37: The epithelial lining is a uniform layer of stratified squamous epithelium. Rete ridges are not a feature.

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F6Ch37: A superficial and basal unit are represented. The granular layer consists of 2 or 3 cell layers. The keratinized debris consists of loosely attached lamellae. The epithelial lining displays the basic features of epidermis.

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